Laron Syndrome

An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

Also Known As:

Syndrome, Laron; Growth Hormone Receptor Defect; Growth Hormone Receptor Deficiency; Laron Dwarfism; Laron Type Dwarfism I; Pituitary Dwarfism II; Primary GH Resistance; Primary Growth Hormone Resistance; Severe GH Insensitivity; Dwarfism II, Pituitary; Dwarfism IIs, Pituitary; Dwarfism, Laron; GH Resistance, Primary; Pituitary Dwarfism IIs; Growth Hormone Insensitivity Syndrome

Musculoskeletal Diseases: 719
- Bone Diseases: 5863
  - Developmental Bone Diseases: 153
    - Dwarfism: 1191
      - Laron Syndrome: 324
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Dwarfism: 1191
    - Laron Syndrome: 324
Endocrine System Diseases: 968
- Dwarfism: 1191
  - Laron Syndrome: 324

German IGF-I Deficiency Study Group Selected Research

German IGF-I Deficiency Study Group Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure